Location History:
- Mewton, MA (US) (2013)
- Newton, MA (US) (1989 - 2017)
Company Filing History:
11 out of 31 
6 out of 9 
1 out of 2 Years Active: 1989-2017
Title: Jerome M Lewis: Innovator in Iron Oxide Complexes
Introduction
Jerome M Lewis is a notable inventor based in Newton, MA (US), recognized for his significant contributions to the field of pharmacological compositions and MRI contrast agents. With a total of 18 patents to his name, Lewis has made remarkable advancements in the development of iron oxide complexes.
Latest Patents
One of his latest patents involves polyol and polyether iron oxide complexes that serve as pharmacological and MRI contrast agents. This patent discloses iron oxide complexes, pharmacological compositions, and methods for their administration, utilizing an iron oxide complex with a polyol. The compositions employ a polysaccharide iron oxide complex, where the polysaccharide is a modified polyol, such as a carboxyalkylated reduced dextran. These complexes are stable to terminal sterilization by autoclaving and are suitable for parenteral administration to treat iron deficiencies or as MRI contrast agents. The complexes are designed to be substantially immunosilent, minimizing the risk of anaphylaxis and undergoing minimal dissolution in vivo. Furthermore, the pharmacological compositions contain minimal free iron, which can be quantified by various methods.
Career Highlights
Throughout his career, Jerome M Lewis has worked with prominent companies such as Advanced Magnetics, Inc. and Amag Pharmaceuticals, Inc. His work has significantly impacted the development of innovative medical solutions.
Collaborations
Lewis has collaborated with notable individuals in his field, including Ernest V Groman and Lee Josephson. Their combined expertise has contributed to the advancement of research in iron oxide complexes.
Conclusion
Jerome M Lewis stands out as a pioneering inventor in the realm of pharmacological compositions and MRI contrast agents. His innovative work continues to influence the medical field, showcasing the importance of research and development in improving healthcare solutions.