The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 1995
Filed:
Jun. 17, 1992
Applicant:
Inventors:
Chu Jung, Arlington, MA (US);
Philip Enriquez, Sheldonville, MA (US);
Stephen Palmacci, Walpole, MA (US);
Lee Josephson, Arlington, MA (US);
Jerome M Lewis, Newton, MA (US);
Assignee:
Advanced Magnetics, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ;
U.S. Cl.
CPC ...
424488 ; 530345 ; 530813 ; 536-111 ; 536-41 ; 5361231 ; 536103 ; 536112 ; 514 54 ; 135178 ;
Abstract
A substantially purified arabinogalactan, its degradative products and selected modifications thereof have been found to act as carriers for delivering therapeutic agent to cell receptors capable of receptor mediated endocytosis (RME). The arabinogalactan and its degrative products once derivatived are capable of forming a complex between the therapeutic agent and the polysaccharide such that the complex retains the ability to recognize and bind to the RME receptor.