Company Filing History:
Years Active: 1992-1995
Title: The Innovations of Stephen Palmacci
Introduction
Stephen Palmacci is an accomplished inventor based in Walpole, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of novel therapeutic agents and materials. With a total of four patents to his name, Palmacci's work has the potential to impact various medical applications.
Latest Patents
Among his latest patents, one notable invention is related to arabinogalactan derivatives and their uses. This invention involves a substantially purified arabinogalactan, its degradative products, and selected modifications that act as carriers for delivering therapeutic agents to cell receptors capable of receptor-mediated endocytosis (RME). The complex formed between the therapeutic agent and the polysaccharide retains the ability to recognize and bind to the RME receptor, enhancing the efficacy of drug delivery.
Another significant patent focuses on the synthesis of polysaccharide-covered superparamagnetic oxide colloids. This method involves creating a colloid that includes a superparamagnetic metal oxide coated with a polymer. The process entails cooling an acidic solution of a metal salt and a polymer, neutralizing it with a cool solution of a base, and applying heat to produce a homogeneous superparamagnetic metal oxide colloid. In this invention, the polymer is preferably a polysaccharide, such as dextran, and the metal salt may include ferrous and ferric salts, resulting in a superparamagnetic iron oxide colloid with an extended plasma half-life.
Career Highlights
Stephen Palmacci is currently associated with Advanced Magnetics, Inc., where he continues to innovate and develop new technologies. His work at the company has been instrumental in advancing the field of magnetic materials and their applications in medicine.
Collaborations
Throughout his career, Palmacci has collaborated with notable colleagues, including Lee Josephson and Chu W Jung. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and the advancement of research.
Conclusion
Stephen Palmacci's contributions to the field of biotechnology through his innovative patents demonstrate his commitment to improving therapeutic delivery systems and materials. His work continues to pave the way for advancements in medical technology and applications.