The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2013
Filed:
Dec. 08, 2010
Ernest V. Groman, Brookline, MA (US);
Kenneth G. Paul, Holliston, MA (US);
Timothy B. Frigo, Waltham, MA (US);
Howard Bengele, Canton, MA (US);
Jerome M. Lewis, Mewton, MA (US);
Ernest V. Groman, Brookline, MA (US);
Kenneth G. Paul, Holliston, MA (US);
Timothy B. Frigo, Waltham, MA (US);
Howard Bengele, Canton, MA (US);
Jerome M. Lewis, Mewton, MA (US);
AMAG Pharmaceuticals, Inc., Lexington, MA (US);
Abstract
Pharmacological compositions, and methods for administration, of the type employing an iron oxide complex with a polyol or polyether. The methods of administration may comprise parenteral administration of an effective dose of the complex formulated in a biocompatible liquid delivered at a rate of from about 1 mL/sec to less than 1 mL/min and wherein upon administration the complex provides minimal detectable free iron in a subject, and minimal incidence of anaphylaxis. The pharmacological compositions are of the type employing a polyol or polyether iron oxide complex, which, upon parenteral administration to a subject, are substantially immunosilent, provide minimal anaphylaxis and minimal free iron, and undergo minimal dissolution in vivo.