Location History:
- Sommerville, NY (US) (1981)
- Somerville, MA (US) (1981 - 1983)
- Brookline, MA (US) (1981 - 2017)
Company Filing History:
24 out of 31 
6 out of 9 
6 out of 809 
Years Active: 1981-2017
Title: Ernest V Groman: Innovations in Pharmacological Compositions
Introduction
Ernest V Groman, based in Brookline, MA, is a notable inventor with an impressive portfolio of 37 patents. His work primarily focuses on iron oxide complexes and their applications in pharmacology and medical imaging, contributing significantly to advancements in these fields.
Latest Patents
Among his latest innovations is the patent for "Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents." This invention outlines iron oxide complexes, pharmacological compositions, and unit dosage methods that employ an iron oxide complex with a polyol. Specifically, the composition involves a polysaccharide iron oxide complex, using a modified polyol such as carboxyalkylated reduced dextran. Notably, the complex is stable to terminal sterilization through autoclaving, making it suitable for parenteral administration to treat iron deficiencies or serve as an MRI contrast agent. The innovation ensures that the complex remains substantially immunosilent, leading to minimal anaphylaxis and limited dissolution in vivo, with pharmacological compositions containing minimal free iron that can be accurately quantified through various methods.
Career Highlights
Ernest has had a distinguished career, contributing his expertise to companies such as Advanced Magnetics, Inc. and Amag Pharmaceuticals, Inc. His experience in these firms has been pivotal in shaping his innovative approaches to pharmaceutical compositions and imaging technologies.
Collaborations
Throughout his career, Ernest has collaborated with notable professionals in his field, including Lee Josephson and Jerome M. Lewis. These partnerships have facilitated the exchange of ideas and enhanced the development of groundbreaking technologies in pharmacological applications.
Conclusion
Ernest V Groman's contributions to the field of pharmacology and medical imaging through his patents represent significant advancements that could have a lasting impact on treatment methodologies and diagnostic imaging techniques. His innovative approach to iron oxide complexes underscores his role as a leading inventor in the industry.