Jeffrey G Mandell

This inventor holds 43 USPTO granted patents and 31 published patent applications, plus 11 CIPO patents and 25 EPO patents, primarily in Nanopore Technology. Top assignees: Illumina Corporation, Ionian Technologies, Inc., Illumina Singapore Pte. Ltd.. Active years: 2017-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Jeffrey G Mandell. Retrieved from https://idiyas.com/inventor/jeffrey-g-mandell

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 43 (Patent Applications = 31)

% Patents Active = 97.7

CIPO Patents = 11 (Patent Applications = 13)

EPO Patents = 25 (Patent Applications = 37)

Average Co-Inventor Count = 3.4

ph-index = 6

Forward Citations = 70(Granted Patents)

Location History:

Rancho Santa Fe, CA (US) (2023)
La Jolla, CA (US) (2017 - 2024)
San Diego, CA (US) (2017 - 2024)

Company Filing History:

Ionian Technologies, Inc.

patents

2 out of 33

Illumina Singapore Pte. Ltd.

patents

4. 2 out of 2,172

University of Washington

patents

5. 1 out of 16,025

University of California

patents

where one patent can have more than one assignee

Years Active: 2017-2026

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Areas of Expertise:

Nanopore Sensors

CRISPR-Cas Systems

Polynucleotide Sequencing

Magnetically-Responsive Sensors

Biochemical Devices

Nucleotide Amplification

Field Effect Transistors

Hybrid Sensors

Event Detection

Polymer Modifications

Genetic Characterization

Nicking Reactions

43 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12662702 - SEQUENCING POLYNUCLEOTIDES USING NANOPORES (2026-06-23),

2. 12625130 - Nanopore sensor devices (2026-05-12),

3. 12612659 - Devices including particles coupled to electrodes, and methods of making and using the same (2026-04-28),

4. 12578321 - Polypeptide nanopores synthetically functionalized with positively charged species, and methods of making and using the same (2026-03-17),

5. 12571037 - Systems and methods using magnetically-responsive sensors for determining a genetic characteristic (2026-03-10),

6. 12391983 - Polynucleotide enrichment and amplification using CRISPR-Cas or Argonaute systems (2025-08-19),

7. 12365939 - Compositions, systems, and methods for detecting events using tethers anchored to or adjacent to nanopores (2025-07-22),

8. 12332248 - Sequence-detection system (2025-06-17),

9. 12065695 - Polynucleotide amplification using CRISPR-Cas systems (2024-08-20),

10. 12050194 - Sensing systems (2024-07-30),

11. 11976322 - Tuning and calibration features of sequence-detection system (2024-05-07),

12. 11970734 - Compositions, systems, and methods for sequencing polynucleotides using tethers anchored to polymerases adjacent to nanopores (2024-04-30),

13. 11898983 - Devices with field effect transistors (2024-02-13),

14. 11879155 - Compositions and methods for polynucleotide sequencing (2024-01-23),

15. 11782006 - Sensing systems (2023-10-10),

Title: Innovations and Contributions of Jeffrey G. Mandell

Introduction

Jeffrey G. Mandell, based in La Jolla, CA, is a prolific inventor with a remarkable portfolio of 35 patents. His work primarily revolves around biotechnological advancements, particularly focusing on nucleic acid amplification and innovative sensing systems. Mandell's contributions have significantly impacted the fields of genetics and molecular diagnostics.

Latest Patents

Among his latest patents, Mandell developed a method for polynucleotide amplification using CRISPR-Cas systems. This innovation provides a system that comprises a crRNA or its derivative along with a Cas protein or its variant. The crRNA contains a target-specific nucleotide region that is substantially complementary to a part of the target nucleic acid, facilitating the formation of a complex when the target nucleic acid is contacted with the system.

Another notable invention is a sophisticated sensing system featuring a pH sensor. This system incorporates two electrodes connected by a conductive channel, onto which a complex is attached. The complex contains a polymerase linked to at least one pH-altering moiety, which generates a pH change close to the conductive channel due to the consumption of a secondary substrate in the fluid exposed to the sensor.

Career Highlights

Mandell has had an impressive career, with significant experience at leading companies in the biotechnology sector, including Illumina Corporation and Ionian Technologies, Inc. His roles in these companies have allowed him to apply his innovative ideas and refine his research in real-world applications.

Collaborations

Throughout his career, Jeffrey G. Mandell has worked alongside notable colleagues such as Kevin L. Gunderson and Jens H. Gundlach. These collaborations have enhanced his research and contributed to the successful development of numerous patents and innovations.

Conclusion

Jeffrey G. Mandell's contributions to the field of biotechnology and molecular science are significant. His innovative patents, particularly in polynucleotide amplification and sensing technologies, position him as a leader in his field. As his career progresses, Mandell continues to push the boundaries of invention and research, inspiring future innovations in technology and science.

Profile summary based on public USPTO records.