The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2024
Filed:
Jan. 24, 2020
Illumina, Inc., San Diego, CA (US);
Jeffrey S. Fisher, San Diego, CA (US);
Brian D. Mather, San Diego, CA (US);
Kaitlin M. Pugliese, San Diego, CA (US);
Jeffrey G. Mandell, La Jolla, CA (US);
Maria Candelaria Rogert Bacigalupo, Encinitas, CA (US);
Boyan Boyanov, San Diego, CA (US);
Illumina, Inc., San Diego, CA (US);
Abstract
In an example, a sensing system includes a pH sensor. The pH sensor includes two electrodes and a conductive channel operatively connected to the two electrodes. A complex is attached to the conductive channel of the pH sensor. The complex includes a polymerase linked to at least one pH altering moiety that is to participate in generating a pH change within proximity of the conductive channel from consumption of a secondary substrate in a fluid that is exposed to the pH sensor. The at least one pH altering moiety is selected from the group consisting of an enzyme, a metal coordination complex, a co-factor, and an activator.