Jae Jun Song

Title: Innovations of Jae Jun Song in Biosensor Technology

Introduction

Jae Jun Song is a prominent inventor based in Daejeon, South Korea. He has made significant contributions to the field of biosensor technology, holding a total of 4 patents. His work focuses on innovative methods for detecting ligands and quantifying enzymatic activities, which have broad applications in biotechnology.

Latest Patents

One of his latest patents is a "Method for detecting ligand using FRET biosensor." This application relates to a method for detecting ligands using a biosensor that applies the FRET (fluorescence resonance energy transfer) phenomenon. The method allows for the simple detection of a ligand in a sample by measuring the FRET of a biosensor under specific critical temperature conditions. It utilizes the reversible unfolding of a ligand-binding protein at temperatures above the critical threshold, with the unfolding level varying based on ligand concentration. This method can be widely applied to various types of FRET biosensors.

Another notable patent is the "Method of screening and quantifying various enzymatic activities using artificial genetic circuits." This method employs a constructed artificial genetic circuit known as GESS (genetic enzyme screening system) for sensing phenolic compounds. It enables the detection and quantification of target enzymatic activities from metagenomes, allowing for the screening of useful genes from diverse genetic communities at a single-cell level in high throughput. The genetic circuit's sensitivity to phenol derivatives can be controlled, making it advantageous for protein engineering technology and molecular evolution.

Career Highlights

Jae Jun Song is affiliated with the Korea Research Institute of Bioscience and Biotechnology, where he continues to advance research in biosensor technology. His innovative approaches have positioned him as a key figure in the field, contributing to both academic and practical advancements.

Collaborations

He has collaborated with notable coworkers, including Seung Goo Lee and Su Lim Choi, further enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Jae Jun Song's contributions to biosensor technology exemplify the innovative spirit of modern science. His patents reflect a commitment to advancing detection methods and enzymatic activity quantification, which are crucial for various applications in biotechnology.