Company Filing History:
Years Active: 2014-2021
Title: Innovator Spotlight: Jae Hee Shin
Introduction
Jae Hee Shin is a remarkable inventor based in Suwon-si, South Korea, with a strong portfolio of six patents. His innovative work primarily focuses on biopharmaceuticals, particularly in enhancing the efficacy and stability of therapeutic proteins.
Latest Patents
Among his latest contributions to the field are two significant patents:
1. **Polypeptide Complex Comprising Non-Peptidyl Polymer Having Three Functional Ends**
This patent discloses a protein complex that includes a physiologically active polypeptide, a dimeric protein, and a non-peptidyl polymer with three functional ends. The unique design allows for the covalent bonding of both the physiologically active polypeptide and dimeric protein to the polymer. The resulting protein complex not only guarantees enhanced biostability but also ensures long-acting activity of the polypeptide. This innovation significantly improves the serum half-life of various physiologically active polypeptide drugs and increases production yield by minimizing raw material loss. Additionally, the complex is designed for easy purification, making it a valuable asset in drug development.
2. **Insulin Conjugate Using an Immunoglobulin Fragment**
This invention presents an insulin conjugate that improves in vivo duration and stability. This conjugate is created by covalently linking insulin with an immunoglobulin Fc region through a non-peptidyl polymer. As a result, the conjugate maintains the in vivo activity of insulin at elevated levels while considerably increasing its serum half-life. This advancement promises to enhance patient compliance during insulin treatment, marking a significant step forward in diabetes care.
Career Highlights
Currently, Jae Hee Shin is a key figure at Hanmi Science Co., Ltd., where he drives innovative research in biopharmaceuticals. His expertise in protein engineering has positioned him as an influential innovator in the field of drug formulation.
Collaborations
Jae Hee works alongside accomplished colleagues, including Dae Hae Song and Se Chang Kwon. Collaborations with these experts further strengthen the research initiatives at Hanmi Science, enhancing the potential for significant breakthroughs in therapeutic applications.
Conclusion
Jae Hee Shin's contributions to the field of biopharmaceuticals exemplify his commitment to advancing medicine through innovative solutions. With his robust patent portfolio and collaborative spirit, he continues to pave the way for developments that significantly impact patient care and treatment efficacy. His work is a testament to the importance of innovation in healthcare and the ongoing need for advancements in drug delivery systems.