The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2014
Filed:
Mar. 18, 2010
Dae Hae Song, Hwaseong-si, KR;
Jae Hee Shin, Suwon-si, KR;
Jae Min Lee, Seoul, KR;
Young Kyung Park, Suwon-si, KR;
SE Chang Kwon, Seoul, KR;
Gwan Sun Lee, Seoul, KR;
Dae Hae Song, Hwaseong-si, KR;
Jae Hee Shin, Suwon-si, KR;
Jae Min Lee, Seoul, KR;
Young Kyung Park, Suwon-si, KR;
Se Chang Kwon, Seoul, KR;
Gwan Sun Lee, Seoul, KR;
Hanmi Science Co., Ltd, Hwaseong-si, KR;
Abstract
The present invention provides a method for preparing a site-specific physiologically active polypeptide conjugate in a high yield by treating a physiologically active polypeptide with a non-peptidyl polymer in the presence of an alcohol at a specific pH, which can be desirably employed in the development of long acting formulations of various peptide drugs having high in-vivo activity and markedly prolonged in-blood half-life.