Company Filing History:
4 out of 15,471 
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Years Active: 1985-1997
Title: The Innovations of Ira Herskowitz
Introduction
Ira Herskowitz is a notable inventor based in Berkeley, CA, who has made significant contributions to the field of molecular biology. With a total of 4 patents, her work primarily focuses on the Origin of Replication Complex (ORC) genes and their applications in pharmacological research.
Latest Patents
Herskowitz's latest patents include innovative methods and compositions related to ORC genes. These patents describe nucleic acids that encode ORC proteins, as well as hybridization reagents, probes, and primers capable of hybridizing with ORC genes. The methods provided are aimed at screening chemical libraries for lead compounds that can be used in the diagnosis or treatment of diseases associated with undesirable cell growth. An exemplary screening process involves forming a mixture that includes a recombinant ORC protein, a natural intracellular ORC protein binding target, and a candidate pharmacological agent. The mixture is incubated under specific conditions to detect the binding of the ORC protein to the target, which is crucial for identifying potential therapeutic agents.
Career Highlights
Throughout her career, Ira Herskowitz has worked with prestigious institutions such as the University of California and Cold Spring Harbor Laboratory. Her research has significantly advanced the understanding of replication processes in cells, contributing to the broader field of genetics and molecular biology.
Collaborations
Herskowitz has collaborated with prominent scientists, including Bruce W. Stillman and Stephen P. Bell. These collaborations have further enriched her research and have led to advancements in the understanding of ORC proteins and their functions.
Conclusion
Ira Herskowitz's contributions to the field of molecular biology through her patents and research collaborations highlight her role as an influential inventor. Her work continues to pave the way for advancements in the diagnosis and treatment of diseases related to cell growth.