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For the Inventor, By the Inventor

Cold Spring Harbor, NY, United States of America

Cold Spring Harbor Laboratory


USPTO Granted Patents = 196

% Expired Patents = 19.9



Trademarks = 13

Forward Citations = 2,623

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263 inventors (with patents filed for the assignee):

goldMedal Michael H Wigler (30 out of 41 patents)

silverMedal Gregory J Hannon (30 out of 32 patents)

bronzeMedal David H Beach (30 out of 34 patents)

4.  Timothy P Tully (16 out of 24 patents)

5.  Nicholas K Tonks (15 out of 15 patents)

6.  Manuel Serrano (12 out of 12 patents)

7.  Scott William Lowe (12 out of 16 patents)

8.  Adrian R Krainer (11 out of 14 patents)

9.  Douglas J Demetrick (9 out of 9 patents)

10.  C Frank Bennett (7 out of 203 patents)

11.  Frank Rigo (7 out of 51 patents)

12.  David Peter Jackson (7 out of 11 patents)

13.  Hajime Sakai (7 out of 51 patents)

14.  Filippo Cavalieri (7 out of 8 patents)

15.  Konstantin Galaktionov (7 out of 9 patents)


Core Competencies:
RNA Interference
Cancer Treatment
Genomic Copy Number
Nucleotide Sequences
ShRNA Design
Neurodegenerative Disorders
Cognitive Deficit
Microrna Production
Transposable Elements
Leukemia Therapy
Phenotypic Modulation
ADP-Ribose Labeling

196 patents:

1. 12601734 - Methods and uses of enzymatic labeling of ADP-ribose containing molecules (2026-04-14),
2. 12516367 - RANDOM NUCLEOTIDE MUTATION FOR NUCLEOTIDE TEMPLATE COUNTING AND ASSEMBLY (2026-01-06),
3. 12497411 - Muscarinic acetylcholine receptor subtype 4 antagonists in the treatment of anemia (2025-12-16),
4. 12378320 - Methods for treating pancreatitis (2025-08-05),
5. 12351802 - Structurally designed shRNAs (2025-07-08),
6. 12326622 - Thermally tunable low broadband waveguides and related systems and methods (2025-06-10),
7. 12270035 - Florigen pathway toolkit (2025-04-08),
8. 12234510 - Varietal counting of nucleic acids for obtaining genomic copy number information (2025-02-25),
9. 12215128 - (Pyridinylmethyl)butanediamine derivatives that chelate copper (2025-02-04),
10. 12178825 - Method and compositions for forming a copper-containing complex and uses thereof (2024-12-31),
11. 12031127 - Multiplexed analysis of neuron projections by sequencing (2024-07-09),
12. 11753641 - Structurally designed shRNAs (2023-09-12),
13. 11739315 - Genetic copy number determination using high throughput multiplex sequencing of smashed nucleotides (2023-08-29),
14. 11660306 - Treatment of Rett syndrome (2023-05-30),
15. 11643665 - Nucleotide sequences encoding Fasciated EAR3 (FEA3) and methods of use thereof (2023-05-09),
Cold Spring Harbor Laboratory, located in Cold Spring Harbor, NY, is a renowned research institution specializing in molecular biology and genetics. The laboratory is at the forefront of RNA interference technology, focusing on its applications in cancer treatment and neurodegenerative disorders. Researchers at CSHL explore genomic copy number variations, nucleotide sequences, and the design of short hairpin RNAs (shRNAs) to advance understanding of cognitive deficits and develop innovative therapeutic strategies.
Profile summary based on public USPTO records.

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USPTO Data Jan 1 1976 - Sep 29 2026

Cold Spring Harbor Laboratory
196 Patents

#1 in Cold Spring Harbor, NY

#136 in New York

#2,098 in US

#4,291 in the World

Cold Spring Harbor, NY (US)
Cold Spring Harbor, NY, United States of America

Cold Spring Harbor Laboratory

Forward Citations = 2,623

263 inventors:

goldMedal Michael H Wigler (30 out of 41 patents)

silverMedal Gregory J Hannon (30 out of 32 patents)

bronzeMedal David H Beach (30 out of 34 patents)

4.  Timothy P Tully (16 out of 24 patents)

5.  Nicholas K Tonks (15 out of 15 patents)

Please report any incorrect information to [email protected]
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