The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2026
Filed:
Apr. 02, 2019
The Johns Hopkins University, Baltimore, MD (US);
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
Anthony K. L. Leung, Ellicott City, MD (US);
Yoshinari Ando, Baltimore, MD (US);
Robert L Mcpherson, Baltimore, MD (US);
Mohsen Badiee, Baltimore, MD (US);
Elad Elkayam, Cold Spring Harbor, NY (US);
THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);
COLD SPRING HARBOR LABORATORY, Cold Spring Harbor, NY (US);
Abstract
Described is ELTA (Enzymatic Labeling of Terminal ADP-ribose) to label free, protein-conjugated, or nucleic acid-conjugated ADP-ribose monomer and polymers at their 2'-OH termini. When coupled with different chemical analogs, ELTA can be used for various applications including fluorescence-based biophysical measurement of PAR-protein interaction, detection of PAR length from cells, and enrichment of ADP-ribosylated peptides for mass spectrometry identification.