Hou-Sen Lim is an inventive force located in Singapore, SG, holding an impressive portfolio of 21 patents. His groundbreaking work primarily focuses on the development of innovative biological heart valves, effectively transforming the landscape of cardiovascular surgery and treatment.

Latest Patents

Among his notable inventions, two recently filed patents stand out for their remarkable methodologies in the preparation of biological heart valves.

1. **Pre-loadable Biological Heart Valve Capable of Rapid Rehydration**: This invention details a method that begins with a cross-linking treatment using an aqueous glutaraldehyde solution to cross-link the biological valve. Following this, a hydrophilic treatment involves soaking the biological valve in a solution containing a hydrophilic molecule and a condensing agent, allowing for the immobilization of the hydrophilic molecule via chemical grafting. The final step is a drying treatment, resulting in a pre-loadable biological heart valve designed for rapid rehydration.

2. **Pre-loadable Dried Biological Heart Valve and Preparation Method Thereof**: This patent outlines a two-step preparation process. Step A involves soaking a fresh animal pericardium in an aqueous solution of soluble elastin or glycosaminoglycan followed by a first cross-linking reaction using carbodiimide or N-hydroxysuccinimide to bind these compounds chemically. Step B consists of a second cross-linking reaction in an aqueous glutaraldehyde solution, with drying of the pericardium thereafter, yielding a robust, dried biological heart valve that is effective in simulated folding and pressing tests.

Career Highlights

Throughout his career, Hou-Sen Lim has made significant contributions to the field of medical technology. He has worked with esteemed companies, including Venus Medtech (Hangzhou) Inc. and Transcatheter Technologies GmbH, where he developed advanced solutions for heart valve technologies.

Collaborations

In his journey toward innovation, Hou-Sen Lim has collaborated with notable professionals such as Wolfgang Goetz and Wolfgang Gotz. These partnerships have fostered an environment of creativity and technological advancement, leading to impactful inventions in the realm of cardiovascular health.

Conclusion

Hou-Sen Lim’s work exemplifies transformative innovation in the medical field, particularly with his pioneering biological heart valve technologies. With his extensive patent portfolio and collaborations, he continues to push the boundaries of what's possible in cardiovascular treatment, reflecting the vital role of inventors in advancing healthcare solutions.

This text is generated by artificial intelligence and may not be accurate.

Please report any incorrect information to support@idiyas.com