This inventor holds 11 USPTO granted patents and 11 published patent applications and 3 EPO patents. Top assignees: Showa Denko K.k., Hokkaido University, Sds Biotech K.k.. Active years: 2003-2021.
Location History:
- Chiba, JP (2003 - 2013)
- Kawasaki, JP (2016)
- Tokyo, JP (2017 - 2021)
Company Filing History:


Years Active: 2003-2021
Title: Hirobumi Aoki: Innovator in Oligonucleotide Separation and Biochemical Manufacturing
Introduction
Hirobumi Aoki is a notable inventor based in Chiba, Japan. He has made significant contributions to the fields of oligonucleotide separation and biochemical manufacturing. With a total of 11 patents to his name, Aoki's work has advanced the methodologies used in these areas.
Latest Patents
One of Aoki's latest patents is a separation and analysis method for a mixture of oligonucleotides. This invention relates to a method of separating and analyzing oligonucleotides through liquid chromatography. The method utilizes a column packed with a packing material obtained by fixing a diol to the surface of porous particles made from a crosslinked organic polymer. This innovative approach allows for higher sensitivity in the separation and analysis of oligonucleotides compared to traditional silica gel columns. Additionally, the column can be effectively washed with an alkaline solution.
Another significant patent involves a manufacturing method for 1,4-butanediol using microbes and specific genes. This method outlines the process of producing 1,4-butanediol through a series of biochemical transformations involving acetyl-CoA and other intermediates. The invention highlights the use of genes with specific base sequences, enhancing the efficiency of the manufacturing process.
Career Highlights
Throughout his career, Hirobumi Aoki has worked with prominent companies such as Showa Denko K.K. and SDS Biotech K.K. His experience in these organizations has contributed to his expertise in the field of biochemistry and innovation.
Collaborations
Aoki has collaborated with notable individuals in his field, including Harumi Kamachi and Yohei Kurata. These partnerships have likely fostered a creative environment for innovation and development.
Conclusion
Hirobumi Aoki's contributions to the fields of oligonucleotide separation and biochemical manufacturing demonstrate his innovative spirit and dedication to advancing technology. His patents reflect a commitment to improving methodologies that have significant implications in research and industry.