The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2021
Filed:
Jun. 21, 2018
Applicant:
Showa Denko K.k., Tokyo, JP;
Inventors:
Assignee:
SHOWA DENKO K.K., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/32 (2006.01); B01J 20/285 (2006.01); G01N 30/34 (2006.01); G01N 30/50 (2006.01); G01N 30/72 (2006.01); G01N 30/74 (2006.01); G01N 30/88 (2006.01); B01D 15/16 (2006.01); B01D 15/42 (2006.01); B01D 15/20 (2006.01); B01J 20/32 (2006.01); C07K 1/20 (2006.01); B01J 20/28 (2006.01);
U.S. Cl.
CPC ...
B01D 15/32 (2013.01); B01D 15/166 (2013.01); B01D 15/20 (2013.01); B01D 15/424 (2013.01); B01J 20/285 (2013.01); B01J 20/3246 (2013.01); C07K 1/20 (2013.01); G01N 30/34 (2013.01); G01N 30/50 (2013.01); G01N 30/72 (2013.01); G01N 30/74 (2013.01); G01N 30/88 (2013.01); B01J 20/28016 (2013.01);
Abstract
The present invention relates to a method of separating and analyzing a mixture of oligonucleotides, including performing liquid chromatography using a column packed with a packing material obtained by fixing a diol to a surface of each of porous particles formed of a crosslinked organic polymer. According to this method, the oligonucleotides can be separated and analyzed with higher sensitivity compared to cases where columns having silica gel as a base material are used. In addition, the column can be washed with an alkaline solution.