Location History:
- Holliston, MA (US) (2010 - 2012)
- South Hamilton, MA (US) (2012 - 2022)
Company Filing History:
Years Active: 2010-2022
Title: The Innovative Contributions of Inventor Herbert Haack
Introduction
Herbert Haack is an accomplished inventor based in South Hamilton, Massachusetts, with a remarkable portfolio of 18 patents to his name. His research focuses on groundbreaking advancements in the field of cancer detection and treatment, particularly related to lung cancer.
Latest Patents
Among Herbert's significant contributions are his latest patents centered around compositions for detecting mutant anaplastic lymphoma kinase in lung cancer. He identified novel gene deletions and translocations involving chromosome 2, resulting in fusion proteins that combine parts of the Anaplastic Lymphoma Kinase (ALK) kinase with secondary proteins, such as Echinoderm Microtubule-Associated Protein-Like 4 (EML-4) and TRK-Fusion Gene (TFG). The EML4-ALK fusion protein, confirmed to drive the proliferation and survival of non-small cell lung carcinoma (NSCLC), is a key highlight of his research. This invention includes isolated polynucleotides and vectors encoding the mutant ALK kinase polypeptides, as well as probes and reagents for detecting the fusion and truncated polypeptides. Another notable area of his research focuses on ROS kinase in lung cancer. He has described polypeptides with ROS kinase activity, including fusion elements with other non-ROS proteins, and has offered methods for screening and inhibiting the progression of lung cancer characterized by these activities.
Career Highlights
Herbert Haack's career has been marked by significant contributions to cancer research, especially in the development of novel methodologies for diagnosing and treating various forms of lung cancer. His work has led to advancements in understanding the molecular basis of these malignancies, which is crucial for improving patient outcomes.
Collaborations
In his journey of innovation, Herbert has collaborated with esteemed colleagues Ting-Lei Gu and Laura Sullivan. Together, they have made substantial contributions in the research landscape, amplifying the impact of their findings in the field of oncology.
Conclusion
Herbert Haack's innovative spirit and dedication to advancing cancer research place him among the notable inventors in the field. With a firm grasp on the molecular underpinnings of lung cancer, he continues to make strides that could significantly affect clinical practices and therapeutic strategies, underscoring the importance of his work at Cell Signaling Technology, Inc.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.