The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2018

Filed:

Apr. 10, 2009
Applicants:

Ting-lei Gu, Woburn, MA (US);

Jiong Wu, Reading, MA (US);

Susan Kane, Beverly, MA (US);

Jian Yu, Hamilton, MA (US);

Herbert Haack, South Hamilton, MA (US);

James Wieler, Exeter, NH (US);

Jun-ming Cai, South Hamilton, MA (US);

Victoria Rimkunas, Somerville, MA (US);

Inventors:

Ting-Lei Gu, Woburn, MA (US);

Jiong Wu, Reading, MA (US);

Susan Kane, Beverly, MA (US);

Jian Yu, Hamilton, MA (US);

Herbert Haack, South Hamilton, MA (US);

James Wieler, Exeter, NH (US);

Jun-Ming Cai, South Hamilton, MA (US);

Victoria Rimkunas, Somerville, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 14/47 (2006.01); C07K 14/485 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); C07K 14/4703 (2013.01); C07K 14/485 (2013.01); G01N 33/57423 (2013.01); G01N 33/57484 (2013.01); C07K 2317/20 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention discloses binding agents to the E746-A750 deletion and the L858R point mutations in the epidermal growth factor receptor (EGFR) molecule, and methods for use thereof, including methods for the diagnosis and treatment of cancer.


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