The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2020
Filed:
Sep. 03, 2015
Applicant:
Cell Signaling Technology, Inc., Danvers, MA (US);
Inventors:
Herbert Haack, South Hamilton, MA (US);
Katherine Eleanor Crosby, Middleton, MA (US);
Victoria McGuinness Rimkunas, Reading, MA (US);
Matthew Ren Silver, Rockport, MA (US);
Assignee:
CELL SIGNALING TECHNOLOGY, INC., Danvers, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 31/4162 (2006.01); A61K 31/4545 (2006.01); A61K 31/517 (2006.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G01N 33/57484 (2013.01); A61K 31/4162 (2013.01); A61K 31/4545 (2013.01); A61K 31/517 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57438 (2013.01); C12Q 2600/112 (2013.01);
Abstract
The invention provides methods to identify, diagnose, and treat kidney cancer through the detection of expression and/or activity of anaplastic lymphoma kinase (ALK). The detection of the presence of a polypeptide with ALK kinase activity (e.g., by detecting expression and/or activity of the polypeptide), identify those kidney cancers that are likely to respond to an ALK-inhibiting therapeutic.