Fitchburg, WI, United States of America

Hazel Holden


 

Average Co-Inventor Count = 4.5

ph-index = 3

Forward Citations = 62(Granted Patents)


Company Filing History:


Years Active: 2002-2023

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14 patents (USPTO):Explore Patents

Title: The Innovative Journey of Hazel Holden

Introduction

Hazel Holden, a distinguished inventor based in Fitchburg, Wisconsin, has made significant contributions to the field of biotechnology. With a remarkable portfolio of 14 patents to her name, she has been at the forefront of inventing innovative solutions, particularly concerning vitamin D compounds.

Latest Patents

Among her latest innovations, Hazel Holden developed a method for the crystallization of (22E)-(24R)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D. This patent discloses effective methods for purifying this compound to obtain it in crystalline form. The procedure involves dissolving the compound in a solvent mixture of ethyl acetate and hexane, allowing crystals to precipitate, and subsequently recovering the crystalline product.

Additionally, she has worked on a patent for (20S)-1α,25-dihydroxy-24,24-difluoro-19-nor-vitamin D analogs, exploring their pharmaceutical applications. These analogs feature two fluorine atom substitutions at the 24 position in the side chain and hold promising potential in the therapeutic landscape.

Career Highlights

Hazel Holden’s career is marked by her commitment to advancing vitamin D research. Her work not only highlights her innovative spirit but also contributes to our understanding and application of vitamin D compounds. By utilizing her expertise, she has bridged the gap between scientific research and practical pharmaceutical applications, making a lasting impact in her field.

Collaborations

Throughout her career, Hazel has collaborated with several esteemed colleagues, including Hector Floyd DeLuca and James Thoden. These partnerships have enhanced the breadth and depth of her research, allowing for a multidisciplinary approach to her inventions and opening new avenues for further innovation.

Conclusion

Hazel Holden exemplifies the spirit of innovation through her groundbreaking inventions and collaborations in the field of vitamin D research. With her ongoing contributions, she continues to inspire future generations of inventors and scientists looking to advance the boundaries of science and technology.

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