The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2013
Filed:
Aug. 17, 2012
Hector F. Deluca, Deerfield, WI (US);
Agnieszka Glebocka, Madison, WI (US);
James B. Thoden, Madison, WI (US);
Hazel M. Holden, Fitchburg, WI (US);
Hector F. DeLuca, Deerfield, WI (US);
Agnieszka Glebocka, Madison, WI (US);
James B. Thoden, Madison, WI (US);
Hazel M. Holden, Fitchburg, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
A method of purifying 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin Dto obtain 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin Din crystalline form. The method includes the steps of preparing a solvent of either ethyl formate or a mixture of ethyl formate and hexane, dissolving a product containing 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin Dto be purified in the solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin Dcrystals, and recovering the 1α-hydroxy-20-methyl-2-methylene-19,24,25,26,27-pentanorvitamin Dcrystals.