The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2013
Filed:
Sep. 28, 2011
Hector F. Deluca, Deerfield, WI (US);
Pawel Grzywacz, Madison, WI (US);
James B. Thoden, Madison, WI (US);
Hazel Holden, Fitchburg, WI (US);
Hector F. DeLuca, Deerfield, WI (US);
Pawel Grzywacz, Madison, WI (US);
James B. Thoden, Madison, WI (US);
Hazel Holden, Fitchburg, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
A method of purifying (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin Dto obtain (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin Din crystalline form. The method includes the steps of preparing a solvent of methanol and water, dissolving a product containing (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin Dto be purified in the solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin Dcrystals, and recovering the (20R,25S)-2-methylene-19,26-dinor-1α,25-dihydroxyvitamin Dcrystals.