Guilford, CT, United States of America

Harold A Mastalerz

USPTO Granted Patents = 24 


 

Average Co-Inventor Count = 5.4

ph-index = 6

Forward Citations = 143(Granted Patents)


Company Filing History:


Years Active: 1999-2021

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24 patents (USPTO):

Title: Harold A. Mastalerz: Innovator in Pharmaceutical Compounds

Introduction

Harold A. Mastalerz, based in Guilford, Connecticut, is a prolific inventor with a remarkable portfolio of 24 patents. His work primarily focuses on developing innovative compounds for therapeutic applications, particularly in the field of oncology and viral infections.

Latest Patents

Among his latest contributions to the scientific community are two groundbreaking patents. The first is centered around isofuranone compounds, which serve as inhibitors of hematopoietic progenitor kinase 1 (HPK1). These compounds, defined by their unique formula, have significant potential in modulating the enzymatic activity of HPK1, thereby offering solutions in treating viral infections and proliferative disorders, including cancer.

The second patent highlights substituted dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-ones, which act as inhibitors for RIPK3, a crucial kinase in various cellular processes. These innovative compounds are designed to have various forms such as enantiomers and stereoisomers and are expected to enhance therapeutic strategies against diseases involving RIPK3 modulation.

Career Highlights

Harold A. Mastalerz is affiliated with Bristol-Myers Squibb Company, a leading global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines. His extensive experience and contributions in pharmaceutical research have positioned him as a key player in the development of novel therapeutic agents.

Collaborations

Throughout his career, Mastalerz has collaborated with notable colleagues, including Ashvinikumar V. Gavai and Guifen Zhang. These collaborations highlight the importance of teamwork and shared expertise in driving innovation in drug development and ensuring the advancement of science in the pharmaceutical arena.

Conclusion

Harold A. Mastalerz exemplifies the spirit of innovation through his extensive work in pharmaceutical development. His patents not only contribute to advancing healthcare but also demonstrate the vital role inventors play in creating solutions for complex medical challenges. As he continues to pursue groundbreaking research, his contributions will undoubtedly leave a lasting impact on the medical community.

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