The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 07, 2010
Filed:
Sep. 24, 2008
Brian E. Fink, Princeton Junction, NJ (US);
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Gregory D. Vite, Titusville, NJ (US);
Ping Chen, Belle Mead, NJ (US);
Harold Mastalerz, Guilford, CT (US);
Derek J. Norris, Pennington, NJ (US);
John S. Tokarski, Princeton, NJ (US);
Yufen Zhao, Pennington, NJ (US);
Wen-ching Han, Newtown, PA (US);
Brian E. Fink, Princeton Junction, NJ (US);
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Gregory D. Vite, Titusville, NJ (US);
Ping Chen, Belle Mead, NJ (US);
Harold Mastalerz, Guilford, CT (US);
Derek J. Norris, Pennington, NJ (US);
John S. Tokarski, Princeton, NJ (US);
Yufen Zhao, Pennington, NJ (US);
Wen-Ching Han, Newtown, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.