The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2021
Filed:
Nov. 05, 2018
Bristol-myers Squibb Company, Princeton, NJ (US);
Erika M. V. Araujo, Woodbridge, CT (US);
Yan Chen, Yardley, PA (US);
Bireshwar Dasgupta, Doylestown, PA (US);
Andrew P. Degnan, Jamison, PA (US);
Matthew D. Hill, Windham, NH (US);
Godwin Kwame Kumi, Morrisville, PA (US);
Harold A. Mastalerz, Guilford, CT (US);
Mark D. Wittman, Hopkinton, MA (US);
Bradley C. Pearce, East Hampton, CT (US);
Guifen Zhang, Hopkinton, MA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are compounds of Formula (I) or a salt thereof, wherein: X is CH or N; Y is CR5 or N; and R1, R2, R3, R4, and R5 are defined herein. Also disclosed are methods of using such compounds to modulate or inhibit the enzymatic activity of hematopoietic progenitor kinase 1 (HPK1), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.