Location History:
- Hosur, IN (2015)
- Nadu, IN (2018)
Company Filing History:
Years Active: 2015-2018
Title: Gokul Jothiraman: Innovator in Recombinant Peptide Expression
Introduction
Gokul Jothiraman is a notable inventor based in Nadu, India. He has made significant contributions to the field of biotechnology, particularly in the expression of recombinant peptides. With a total of two patents to his name, Gokul's work has the potential to impact various applications in the industry.
Latest Patents
Gokul's latest patents include a comprehensive model for the expression of recombinant peptides. This model utilizes a controllable variable known as the 'critical nutrient ratio' to achieve an optimal balance between product synthesis and degradation during the fermentation process. By controlling this ratio and incorporating soya flour hydrolysate and EDTA, the extracellular concentration of precursors can be increased by approximately tenfold, while degradation constants can be reduced by 10-20 times for both intracellular and extracellular cases.
Another significant patent involves novel Prolipase-Bovine trypsinogen (PLBTR) fusion proteins. This invention details methods for producing PLBTR fusion proteins in optimal quantities, which include a heterologous polypeptide that is typically susceptible to autocatalytic activity. The patent outlines the fusion of a serine protease to a lipase signal sequence, allowing for expression by recombinant host cells in desired amounts. Additionally, it covers polynucleotides encoding these fusion proteins, expression vectors, and methods for generating such proteins.
Career Highlights
Gokul Jothiraman is currently employed at Biocon Limited, a leading biopharmaceutical company. His work at Biocon has allowed him to further develop his innovative ideas and contribute to advancements in biotechnology.
Collaborations
Gokul collaborates with talented individuals such as Sanjay Tiwari and Gourav Awasthi. Their teamwork fosters a creative environment that enhances the development of innovative solutions in their field.
Conclusion
Gokul Jothiraman is a prominent inventor whose work in recombinant peptide expression showcases his innovative spirit and dedication to biotechnology. His patents reflect a commitment to advancing the field and improving production methods, which could lead to significant advancements in various applications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.