Company Filing History:
Years Active: 2015-2021
Title: Frances Louise Stites: Innovator in Detection Technologies
Introduction
Frances Louise Stites is a notable inventor based in Ashburn, VA, with a significant contribution to the field of detection technologies. She holds four patents, showcasing her innovative approach to solving complex problems in the detection of harmful substances.
Latest Patents
One of her latest patents involves methods and systems for the detection of ricin and other ribosome inactivating proteins. This invention includes a device, method, and system for detecting ribosome inactivating protein activity, such as the ricin toxin, in a sample. The process utilizes a labeled DNA substrate that, when acted upon by the ribosome inactivating protein, creates an abasic site. An AP lyase cleaves the DNA substrate at this site, allowing a fluorophore and a quencher to spatially separate, resulting in an emitted fluorescence signal that indicates ribosome inactivating protein activity. This detection is monitored in real time using a specialized detection system.
Another significant patent focuses on detecting a target molecule in a sample using a dual-antibody quantitative fluorescence-based detection method. This kit and method include an assay mixture with probes that recognize specific epitopes of the target, along with a reverse primer and reverse transcriptase. The method ensures that if the target is present, the RNA and DNA oligonucleotides are brought into close proximity, facilitating the detection process.
Career Highlights
Frances has worked with several companies, including Src Corporation and Acumen Detection, Inc. Her work in these organizations has contributed to advancements in detection technologies, particularly in the context of public health and safety.
Collaborations
Some of her notable coworkers include Kenton Arthur Doctor and Stacey Ann Massulik, who have collaborated with her on various projects, enhancing the impact of her inventions.
Conclusion
Frances Louise Stites is a pioneering inventor whose work in detection technologies has made significant strides in identifying harmful substances. Her innovative patents reflect her commitment to advancing safety and health through scientific discovery.