The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Dec. 12, 2014
Src, Inc., North Syracuse, NY (US);
Kenton Arthur Doctor, East Syracuse, NY (US);
Stacey Ann Massulik, Syracuse, NY (US);
Frances Louise Stites, Ashburn, VA (US);
Timothy Francis Moshier, Volney, NY (US);
Jeffrey Harold Mills, Liverpool, NY (US);
Lisa Helen Chamberlin, East Syracuse, NY (US);
Deborah Lynne Plochocki, Marcellus, NY (US);
Olivia Jennifer Barrett, Cicero, NY (US);
Huda Sirageldin Suliman, North Syracuse, NY (US);
SRC, Inc., North Syracuse, NY (US);
Abstract
A real-time portable and rapid detection assay to identify the presence of biologically active toxins such as botulinum toxins. The proteolytic activity of BoNT/A is measured using a peptide cleavage assay, where a fluorescent substrate is cleaved by BoNT/A, resulting in increased fluorescence. This fluorescence can be monitored in real-time using a fluorescence detection instrument, such as a real-time PCR system that has been modified to implement a detection algorithm specific to the identification of the target toxin.