Location History:
- Milan, IT (1993 - 2004)
- Lodi, IT (1991 - 2024)
Company Filing History:
4 out of 142 
2 out of 65 
2 out of 260 
Years Active: 1991-2024
Title: The Innovative Contributions of Federico Maisano
Introduction: Federico Maisano is a distinguished inventor based in Lodi, Italy, renowned for his innovative work in the field of recombinant proteins. With a total of 12 patents to his name, his research significantly contributes to advancements in biotechnology and molecular medicine.
Latest Patents: Among his latest innovations is a groundbreaking recombinant chimeric protein designed for selectins targeting. This invention features a PSGL-1-NRL chimeric protein, which includes a Selectin Binding domain and a non-covalent dimerization domain, specifically a leucine zipper that can originate from either human or mouse neural retina-specific leucine zipper. Further enhancements of the chimeric protein include a covalent dimerization domain with at least one cysteine capable of forming a disulfide bridge with another chimeric protein, thus creating a homodimer. The PSGL-1 domain in the chimeric protein represents the extracellular region of Human PSGL-1, focusing on the selectin binding region of the mature protein. Additionally, the protein undergoes correct post-translational modifications to ensure it is efficiently expressed in mammalian systems. It is sulfated, O-linked glycosylated, and sialylated, allowing it to bind P, E, and L selectins, thus enabling both in vivo and in vitro targeting for diagnostic or therapeutic applications.
Career Highlights: Throughout his career, Federico Maisano has made substantial contributions while working at prestigious companies such as Bracco Imaging S.p.A. and Dibra S.p.A. His expertise in the field of biotechnology and protein engineering has been vital in forwarding research and product development within these organizations.
Collaborations: In his journey as an inventor, Federico has collaborated with notable colleagues, including Federico Crivellin and Luigia Gozzini. These partnerships have fostered innovation and enhanced the impact of their collective research.
Conclusion: Federico Maisano stands out as a prominent inventor whose contributions in recombinant protein research demonstrate the potential for significant advancements in medical diagnostics and therapies. His body of work continues to inspire future innovations in biotechnology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.