The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2020
Filed:
Apr. 10, 2018
Applicant:
Bracco Imaging Spa, Milan, IT;
Inventors:
Luciano Lattuada, Cassina de' Pecchi, IT;
Federica Buonsanti, Turin, IT;
Federico Crivellin, Caselle Torinese, IT;
Fulvio Ferretti, Feletto Canavese, IT;
Federico Maisano, Lodi, IT;
Laura Orio, Turin, IT;
Lorena Pizzuto, San Francesco al Campo, IT;
Assignee:
BRACCO IMAGING SPA, Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/18 (2006.01); A61K 49/00 (2006.01); C09B 23/08 (2006.01);
U.S. Cl.
CPC ...
C07D 471/18 (2013.01); A61K 49/0032 (2013.01); A61K 49/0056 (2013.01); C09B 23/083 (2013.01);
Abstract
The application relates to a process for the synthesis of a Near Infra-Red (NIR) fluorescent probe which is a cRGD-Cy5.5 conjugate of formula (I) known as DA364 comprising an aza-bicycloalkane based cyclic peptide labelled with a Cy5.5 dye moiety and used in the guided surgery of tumors and pathologic regions.