Location History:
- Bethesda, MD (US) (2017)
- Washington, DC (US) (2019 - 2020)
- Potomac, MD (US) (2020)
- Rockville, MD (US) (2017 - 2022)
Company Filing History:
5 out of 47 
3 out of 3,539 
3 out of 63 
Years Active: 2017-2022
Title: Fabiola Cecchi: Innovator in Medical Research
Introduction
Fabiola Cecchi is a prominent inventor based in Washington, DC, known for her significant contributions to medical research. With a total of 11 patents to her name, she has made remarkable strides in the field of biotechnology and cancer treatment. Her work focuses on developing innovative solutions to combat diseases characterized by pathological angiogenesis and improving chemotherapy outcomes for colorectal cancer patients.
Latest Patents
Among her latest patents, Fabiola has developed vascular endothelial growth factor antagonists. This invention provides variant VEGF polypeptides that have been altered in their C-terminal heparin binding region to lower their heparin binding affinity. These variants act as receptor antagonists for VEGF receptors and effectively antagonize angiogenesis, making them useful in treating diseases associated with abnormal blood vessel growth. Additionally, she has created methods for predicting optimal chemotherapy for colorectal cancer (CRC). These methods identify whether a cancer patient will respond positively to the FOLFOX regimen, which includes 5-fluorouracil, leucovorin, and oxaliplatin. By detecting specific TYMP and UCK2 fragment peptides in tumor cells, her approach allows for personalized treatment strategies.
Career Highlights
Fabiola has worked with notable organizations such as Expression Pathology Incorporated and the National Institutes of Health, a component of the US Department of Health & Human Services. Her experience in these institutions has significantly contributed to her expertise in medical research and innovation.
Collaborations
Throughout her career, Fabiola has collaborated with esteemed colleagues, including Todd Hembrough and Donald P Bottaro. These partnerships have fostered a collaborative environment that enhances the development of groundbreaking medical solutions.
Conclusion
Fabiola Cecchi's innovative work in medical research exemplifies her dedication to improving patient outcomes through her inventions. Her contributions to the field continue to pave the way for advancements in cancer treatment and biotechnology.