The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Feb. 12, 2019
Applicant:
Nantomics, Llc, Culver City, CA (US);
Inventors:
Todd A. Hembrough, Gaithersburg, MD (US);
Fabiola Cecchi, Potomac, MD (US);
Dongyao Yan, Rockville, MD (US);
Assignee:
NantOmics, LLC, Culver City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 31/4188 (2006.01); A61K 31/495 (2006.01); A61P 35/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57407 (2013.01); A61K 31/4188 (2013.01); A61K 31/495 (2013.01); A61P 35/00 (2018.01); C12Y 201/01063 (2013.01); G01N 33/5088 (2013.01); G01N 33/57484 (2013.01); G01N 2333/91017 (2013.01);
Abstract
Methods are provided for treating a cancer patient suffering from a glioblastoma (GBM) by administering to the patient an effective amount of temozolomide, wherein a mass spectrometry analysis of a protein digest of a formalin-fixed tumor sample from the patient evidences an amount of a MGMT fragment peptide less than or substantially equal to 150 amol/μg.