The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2020
Filed:
Feb. 12, 2019
Applicant:
Nantomics, Llc, Culver City, CA (US);
Inventors:
Todd A. Hembrough, Gaithersburg, MD (US);
Fabiola Cecchi, Potomac, MD (US);
Dongyao Yan, Rockville, MD (US);
Assignee:
NantOmics, LLC, Culver City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7072 (2006.01); A61K 31/282 (2006.01); G01N 33/574 (2006.01); A61P 35/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7072 (2013.01); A61K 31/282 (2013.01); A61P 35/00 (2018.01); G01N 33/57419 (2013.01); G01N 33/6851 (2013.01); G01N 2496/00 (2013.01); G01N 2560/00 (2013.01);
Abstract
Improved methods for treating cancer are provided herein by determining if a cancer patient, particularly a colon cancer patient or a gastric cancer patient, will clinically respond in a favorable manner to a therapeutic strategy comprising the FOLFOX regimen (fluorouracil, leucovorin, and oxaliplatin) or a combination of capecitabine and cisplatin. Diagnostic methods for measuring the OPRT, TYMP, and/or UCK2 proteins in a tissue sample, such as a tumor sample, from the patient are provided.