Location History:
- Washington, DC (US) (1996 - 2003)
- Olney, MD (US) (1997 - 2008)
Company Filing History:
25 out of 676 
3 out of 2,198 
1 out of 4 Years Active: 1996-2008
Title: Innovations and Contributions of Ewen F. Kirkness
Introduction: Ewen F. Kirkness is a distinguished inventor based in Olney, MD, with a remarkable portfolio of 31 patents. His innovative work primarily focuses on biotechnological advancements, particularly in the realm of receptor biology and therapeutic applications.
Latest Patents: Among his latest patents, Kirkness has developed groundbreaking inventions related to the GABA receptor epsilon subunit (GABRE) and its alternative transcript (ET2). This invention encompasses isolated nucleic acid molecules encoding the human GABRE and ET2 receptor subunits, along with related polypeptides. The techniques developed include vectors, host cells, and methods for producing these compounds, and they open pathways for identifying agonists and antagonists of GABRE and ET2 activities. Furthermore, his work includes methods for diagnosing GABRE and ET2 expression anomalies, alongside therapeutic techniques for treating disorders associated with these receptors. Another significant patent involves a human osteoclast-derived cathepsin (referred to as Cathepsin O), which addresses bone diseases like osteoporosis and cancer metastasis through novel therapeutic strategies.
Career Highlights: Ewen Kirkness has significantly contributed to the biotechnology sector, with his extensive experience at Human Genome Sciences, Inc. His career is notable for both his innovative research and his role in advancing the understanding of complex biological mechanisms through his patents.
Collaborations: Throughout his career, Kirkness has collaborated with notable figures in the field, including Mark D. Adams and Claire M. Fraser. These partnerships have facilitated the advancement of his research and the development of impactful technologies.
Conclusion: Ewen F. Kirkness stands out as a prominent inventor whose innovations in receptor biology and therapeutic methods continue to shape the landscape of biotechnology. His extensive patent portfolio demonstrates his commitment to improving human health through scientific ingenuity.