The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2002
Filed:
Jun. 06, 1995
William A. Haseltine, Washington, DC (US);
Steven M. Ruben, Olney, MD (US);
Ying-Fei Wei, Darnestown, MD (US);
Mark D. Adams, North Potomac, MD (US);
Robert D. Fleischmann, Gaithersburg, MD (US);
Claire M. Fraser, Potomac, MD (US);
Rebecca A. Fuldner, Barnesville, MD (US);
Ewen F. Kirkness, Olney, MD (US);
Craig A. Rosen, Laytonsville, MD (US);
Human Genome Sciences, Inc., Rockville, MD (US);
Abstract
The invention discloses three human DNA repair proteins and DNA (RNA) encoding such proteins and a procedure for producing such proteins by recombinant techniques. One of the human DNA repair proteins, hMLH1, has been mapped to chromosome 3 while hMLH2 has been mapped to chromosome 2 and hMLH3 has been mapped to chromosome 7. The polynucleotide sequences of the DNA repair proteins may be used for therapeutic and diagnostic treatments of a hereditary susceptibility to cancer.