Craig A Rosen

Craig A Rosen is an accomplished inventor and researcher based in Laytonsville, MD (US). With an impressive 303 patents to his name, Rosen has made significant contributions to the field of biotechnology and pharmaceuticals. His latest patents showcase his expertise in developing innovative treatments and therapies.

One of Rosen's recent inventions is related to albumin fusion proteins. These proteins, along with the nucleic acid molecules encoding them, have diverse applications in the fields of medicine and molecular biology. This patent covers the creation of these fusion proteins, their nucleic acid sequences, vectors containing these sequences, and methods of producing and utilizing them for the treatment, prevention, or amelioration of various diseases, disorders, or conditions.

Another notable patent by Rosen focuses on Death Domain Containing Receptor-4 (DR4) antibodies and their associated methods. DR4 proteins are essential members of the tumor necrosis factor receptor family. The patent describes the isolation of nucleic acid molecules encoding human DR4 proteins, as well as the production of DR4 polypeptides using recombinant methods. Additionally, the patent encompasses screening methods for identifying DR4 agonists and antagonists, and the use of DR4 antibodies for treating diseases associated with abnormal levels of apoptosis.

Throughout his career, Rosen has collaborated with esteemed colleagues, including Steven M Ruben and Jian Ni. His research and inventions have been affiliated with renowned institutions and companies such as Human Genome Sciences Inc. and the University of Michigan.

Craig A Rosen's contributions to the field of biotechnology and pharmaceuticals have undoubtedly left a significant impact. His patents further enhance our understanding and provide innovative solutions to combat various diseases and disorders.