The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 29, 2016

Filed:

Aug. 07, 2007
Applicants:

Adam C. Bell, Germantown, MA (US);

Craig A. Rosen, Laytonsville, MA (US);

Indrajit Sanyal, Bethesda, MA (US);

Qinghai Zhao, Gaithersburg, MA (US);

Inventors:

Adam C. Bell, Germantown, MA (US);

Craig A. Rosen, Laytonsville, MA (US);

Indrajit Sanyal, Bethesda, MA (US);

Qinghai Zhao, Gaithersburg, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); C07K 14/62 (2006.01); C12N 15/17 (2006.01); A61P 5/50 (2006.01); A61P 3/10 (2006.01); C12N 15/62 (2006.01); C07K 14/765 (2006.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); A61K 38/28 (2013.01); C07K 14/765 (2013.01); C12N 15/62 (2013.01); C07K 2319/35 (2013.01);
Abstract

Disclosed are fusion proteins that include albumin fused to a polypeptide that has insulin activity. The fusion proteins may include albumin fused to insulin or an insulin analog. In particular, the fusions proteins may include albumin fused to a single chain insulin analog. The fusion proteins may exhibit extended insulin activity in vivo or in vitro relative to insulin that is not fused to albumin. The fusion proteins may be formulated as aerosol compositions.


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