The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2002
Filed:
Feb. 12, 1997
Gregg A. Hastings, Rockville, MD (US);
Mark D. Adams, Potomac, MD (US);
Claire M. Fraser, Gueenstown, MD (US);
Norman H. Lee, Woodstock, MD (US);
Ewen F. Kirkness, Washington, DC (US);
Judith A. Blake, Laurel, MD (US);
Lisa M. Fitzgerald, Germantown, MD (US);
Fred H. Drake, Glenmoore, PA (US);
Maxine Gowan, Valley Forge, PA (US);
Other;
Abstract
Disclosed is a human osteoclast-derived cathepsin (Cathepsin O) polypeptide and DNA(RNA) encoding such cathepsin O polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques. The present invention also discloses antibodies, antagonists and inhibitors of such polypeptide which may be used to prevent the action of such polypeptide and therefore may be used therapeutically to treat bone diseases such as osteoporosis and cancers, such as tumor metastases.