The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2002

Filed:

Jan. 27, 1994
Applicant:
Inventors:

Mark D. Adams, North Potomac, MD (US);

Robert D. Fleischmann, Washington, DC (US);

Claire M. Fraser, Queenstown, MD (US);

Rebecca A. Fuldner, Barnesville, MD (US);

Ewen F. Kirkness, Washington, DC (US);

William A. Haseltine, Washington, DC (US);

Craig A. Rosen, Laytonsville, MD (US);

Steve Ruben, Olney, MD (US);

Ying-Fei Wei, Darnestown, MD (US);

Assignee:

Human Genome Sciences, Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 2/102 ; C12N 1/00 ; C12N 1/20 ; C12N 5/10 ;
U.S. Cl.
CPC ...
C12P 2/102 ; C12N 1/00 ; C12N 1/20 ; C12N 5/10 ;
Abstract

The present invention discloses three human DNA repair proteins and DNA (RNA) encoding such proteins. The DNA repair proteins may be produced by recombinant DNA techniques. One of the human DNA repair proteins, hmlh1, has been mapped on chromosome 3. The polynucleotide sequences of DNA repair proteins may be used for diagnosis of a hereditary susceptibility to cancer.


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