Erling Feng

Title: Erling Feng: Innovator in Immunogenic Proteins

Introduction

Erling Feng is a notable inventor based in Beijing, China. He has made significant contributions to the field of biotechnology, particularly in the development of immunogenic proteins and their applications. With a total of three patents to his name, Feng's work has the potential to impact vaccine development and infectious disease treatment.

Latest Patents

Feng's latest patents include an immunogenic protein and its composition and application. This invention discloses a protein that comprises 39 amino acids from the N-terminal α-helix part of the Ata protein transport functional domain. The amino acid sequence of these 39 amino acids is shown as the 127-165 amino acid residues of SEQ ID NO:2. The invention involves fusing these amino acids with CTB and expressing them in BL21. The protein was purified using a nickel column and used to intraperitoneally immunize mice at a dosage of 2.5 μg/mouse. The immunogenicity and immunoprotection were verified through animal experiments, demonstrating its effectiveness in combating infections. Another patent involves a method for preparing a bacterial polysaccharide-modified recombinant fusion protein. This method includes co-expressing a recombinant fusion protein and the O-oligosaccharyltransferase PglL in a gene-defective bacterium, linking polysaccharides to the recombinant fusion protein. This protein can be utilized for preparing antibodies against bacterial polysaccharides and vaccines.

Career Highlights

Feng has worked at prominent institutions, including the Institute of Biotechnology at the Academy of Military Medical Sciences in China and Chengdu Olymvax Biopharmaceuticals Inc. His experience in these organizations has allowed him to advance his research and contribute to significant innovations in the field.

Collaborations

Feng has collaborated with notable colleagues, including Jun Wu and Chao Pan. Their joint efforts have likely enhanced the quality and impact of their research projects.

Conclusion

Erling Feng is a distinguished inventor whose work in immunogenic proteins has the potential to revolutionize vaccine development and infectious disease management. His contributions to biotechnology are noteworthy and continue to influence the field.