Defiance, MO, United States of America

Deborah A Mischke


Average Co-Inventor Count = 11.1

ph-index = 9

Forward Citations = 341(Granted Patents)

Forward Citations (Not Self Cited) = 236(Oct 12, 2025)


Inventors with similar research interests:


Location History:

  • Creve Coeur, MO (US) (1986)
  • Ballwin, MO (US) (2004)
  • Defiance, MI (US) (2004)
  • Defiance, MO (US) (1994 - 2010)

Company Filing History:


Years Active: 1986-2010

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57 patents (USPTO):Explore Patents

Title: **Innovative Contributions of Deborah A. Mischke in Pharmaceutical Patents**

Introduction

Deborah A. Mischke, based in Defiance, MO, is a prolific inventor with a remarkable portfolio of 57 patents. Her work primarily focuses on pharmaceutical innovations aimed at combating various medical conditions, particularly those related to cardiovascular health.

Latest Patents

Among her notable inventions is a patent for (R)-chiral halogenated substituted fused heterocyclic amino compounds that are useful in inhibiting cholesterol ester transfer protein (CETP) activity. This invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds, which serve as inhibitors of CETP, a crucial plasma lipid transfer protein. The patent also describes methods and compounds for treating atherosclerosis and other coronary artery diseases. The innovative processes she developed ensure high yield and stereoselectivity in preparing these chiral substituted alkanol compounds from both chiral and achiral intermediates.

Career Highlights

Deborah has made significant contributions to the pharmaceutical field throughout her career. She has worked with prestigious organizations, including Pharmacia Corporation and G.D. Searle & Company, where she has further honed her skills in drug development and innovation. Her expertise in creating effective pharmaceutical compounds has positioned her as a leader in her field.

Collaborations

Throughout her career, Deborah has collaborated with notable professionals, including Yvette M. Fobian and William F. Vernier. These partnerships have contributed to her success and further advanced the developments of pharmaceutical inventions that enhance patient care and treatment options.

Conclusion

Deborah A. Mischke's extensive patent portfolio and dedication to pharmaceutical innovation showcase her significant role in advancing medical science. Her inventions not only reflect her creativity but also her commitment to developing solutions for pressing health challenges, particularly in the area of cardiovascular health.

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