The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 07, 2004

Filed:

Dec. 16, 2002
Applicant:
Inventors:

James A. Sikorski, Des Peres, MO (US);

Richard C. Durley, Chesterfield, MO (US);

Margaret L. Grapperhaus, Troy, IL (US);

Deborah A. Mischke, Defiance, MO (US);

Emily J. Reinhard, Chesterfield, MO (US);

Barry L. Parnas, University City, MO (US);

Melvin L. Rueppel, St. Louis, MO (US);

Assignee:

Pfizer, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1137 ; C07C / ;
U.S. Cl.
CPC ...
A61K 3/1137 ; C07C / ;
Abstract

The invention relates to substituted N-Alkyl/Alkenyl/Cycloalkyl/Heterocycyl N-Aryl/Heteroaryl tertiary-Heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery disease. Preferred tertiary-heteroalkylamine compounds are substituted N-cycloalkyl N-benzyl aminoalcohols. A specific N-cycloalkyl N-benzyl aminoalcohol is the compound:


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