Company Filing History:
9 out of 110 
6 out of 138 
1 out of 7 Years Active: 1997-2017
Title: David Sweedler: A Pioneer in Nucleic Acid Innovations
Introduction
David Sweedler, located in Louisville, Colorado, is an accomplished inventor renowned for his contributions to the field of molecular biology. With an impressive portfolio of 16 patents, he has made significant strides in developing innovative solutions related to nucleic acids.
Latest Patents
Among his latest inventions is the patent for "Long interfering nucleic acid duplexes targeting multiple RNA targets." This invention involves long interfering nucleic acid (iNA) duplexes that are at least 30 nucleotides in length. These duplexes feature at least one nick or nucleotide gap in the strands, ensuring they do not induce an interferon response when transfected into mammalian cells. Notably, the antisense strands of these duplexes can target two separate mRNAs or two segments of a single mRNA, enabling versatile applications in gene regulation.
Another significant patent is for "Compositions for the delivery of negatively charged molecules." This invention includes permeability enhancer molecules and methods to increase membrane permeability for various molecules, including nucleic acids and proteins. By facilitating cellular uptake, this innovation impacts therapeutic approaches in gene delivery and molecular medicine.
Career Highlights
David Sweedler's professional journey includes impactful roles in leading organizations such as Ribozyme Pharmaceuticals, Incorporated and Sirna Therapeutics, Inc. His work in these companies has shaped the landscape of RNA technology and therapeutic development, assisting in the advancement of new treatment paradigms.
Collaborations
Throughout his career, David has collaborated with prominent scientists such as Leonid Beigelman and Alexander Karpeisky. These collaborative efforts have resulted in groundbreaking advancements in nucleic acid research and applications, underscoring David's role as a pivotal figure in the field.
Conclusion
David Sweedler's innovative work in nucleic acid technology positions him as a leader in molecular biology innovation. His 16 patents not only reflect his ingenuity but also promise to influence future developments in gene therapy and molecular medicine. With a career marked by significant collaborations and contributions, he continues to inspire the next generation of inventors in the scientific community.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.