The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2017
Filed:
Aug. 14, 2015
Applicant:
Biomics Biotechnologies Co., Ltd., Nantong, CN;
Inventors:
Assignee:
BIOMICS BIOTECHNOLOGIES CO., LTD, Nantong, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); C12N 15/111 (2013.01); C12N 15/1136 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/341 (2013.01); C12N 2310/351 (2013.01); C12N 2310/51 (2013.01); C12N 2310/53 (2013.01); C12N 2310/531 (2013.01);
Abstract
Long interfering nucleic acid (iNA) duplexes, which are at least 30 nucleotides in length, which have at least one nick or nucleotide gap in the antisense or the sense strands or in both the sense and antisense strands. These long iNA duplexes do not induce an interferon response when transfected into mammalian cells. The antisense strands can target two separate mRNAs or two segments of one mRNA.