Location History:
- Rehovot, IL (2017 - 2020)
- Rehovot, IL (US) (2023)
Company Filing History:
Years Active: 2017-2025
Title: The Innovative Contributions of David Margulies
Introduction
David Margulies is a prominent inventor based in Rehovot, Israel. He has made significant contributions to the field of fluorescent probes and sensors, holding a total of seven patents. His work focuses on developing advanced technologies that enhance the detection and labeling of proteins in their native environments.
Latest Patents
One of his latest patents is titled "Quinoline based cyanine dye turn-on fluorescent probes and methods of use thereof." This invention is directed to a turn-on fluorescent probe, wherein said probe comprises a quinoline based cyanine dye derivative (QBC) and a specific protein binder covalently attached thereto directly or via a linker. This invention further describes methods for using these turn-on probes and compounds for detecting and labeling a wide range of proteins in their native environment. Another notable patent is "Universal histidine-tag binding compounds and methods of use thereof as fluorescent probes and sensors." This invention is directed to His-tag binding compounds and uses thereof in the preparation of genetically targeted detectable molecules and sensors which can specifically bind tag-labeled proteins. It also provides a system comprising recombinant cells decorated with various labels and/or synthetic agents, wherein said labels and/or synthetic agents can be reversibly modified or removed from the cells.
Career Highlights
David Margulies is associated with Yeda Research and Development Co. Ltd., where he continues to innovate and contribute to scientific advancements. His work has been instrumental in developing technologies that have practical applications in various fields, including biotechnology and molecular biology.
Collaborations
He has collaborated with notable colleagues such as Leila Motiei and Linor Unger, further enhancing the impact of his research and inventions.
Conclusion
David Margulies is a distinguished inventor whose work in fluorescent probes and sensors has significantly advanced the field. His innovative patents and collaborations reflect his commitment to scientific progress and the development of new technologies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.