The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Jun. 14, 2015
Applicant:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Inventors:
Assignee:
YEDA RESEARCH AND DEVELOPMENT CO. LTD., Rehovot, IL;
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); G01N 33/573 (2006.01); C07D 417/06 (2006.01); C09K 11/06 (2006.01); G01N 33/58 (2006.01); C07F 9/6541 (2006.01); C07K 7/06 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); C07F 9/6541 (2013.01); C07K 7/06 (2013.01); C09K 11/06 (2013.01); G01N 33/582 (2013.01); C09K 2211/1029 (2013.01); C09K 2211/1037 (2013.01); G01N 33/574 (2013.01); G01N 2333/918 (2013.01); G01N 2333/91177 (2013.01); G01N 2333/96494 (2013.01);
Abstract
The present invention is directed to fluorescent molecular sensor based on Thiazole Orange for protein detection. Interaction of the protein target with the molecular sensors of this invention results in a significant increase in the fluorescence emission. The generation of light output signal enables one to detect protein biomarkers associated with different diseases or detecting the protein of interest also in living cells.