David Entwistle

Title: The Innovative Contributions of David Entwistle

Introduction

David Entwistle is a prominent inventor based in San Carlos, CA, known for his significant contributions to the field of biotechnology. With a total of 18 patents to his name, he has made remarkable advancements in enzyme engineering and chiral compound synthesis. His work has had a profound impact on various industries, particularly in the development of new methods for producing valuable compounds.

Latest Patents

Among his latest patents, Entwistle has developed engineered ketoreductase polypeptides for the synthesis of chiral compounds. This innovation provides engineered ketoreductase enzymes that exhibit improved properties compared to naturally occurring wild-type enzymes. Additionally, he has created polynucleotides encoding these engineered enzymes, host cells capable of expressing them, and methods for synthesizing a variety of chiral compounds. Another notable patent involves engineered glycosyltransferases and steviol glycoside glucosylation methods. This invention includes engineered glycosyltransferase enzymes, polypeptides with glycosyltransferase activity, and polynucleotides encoding these enzymes. Furthermore, it provides methods for producing rebaudiosides, which are important in the food industry.

Career Highlights

David Entwistle has worked with notable companies such as Codexis, Inc. and Tate & Lyle Solutions USA LLC. His experience in these organizations has allowed him to apply his innovative ideas and contribute to the advancement of biotechnology. His work has not only led to numerous patents but has also paved the way for new applications in various sectors.

Collaborations

Throughout his career, Entwistle has collaborated with talented individuals, including Ravi David Garcia and Nikki Dellas. These collaborations have fostered a creative environment that has led to groundbreaking innovations in enzyme engineering and biotechnology.

Conclusion

David Entwistle's contributions to the field of biotechnology through his patents and collaborations highlight his role as a leading inventor. His work continues to influence the development of new technologies and methods in the industry.