The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Mar. 08, 2023
Applicant:

Codexis, Inc., Redwood City, CA (US);

Inventors:

Jovana Nazor, Milpitas, CA (US);

Robert Osborne, Raleigh, NC (US);

Jack Liang, South San Francisco, CA (US);

Jonathan Vroom, South San Francisco, CA (US);

Xiyun Zhang, Fremont, CA (US);

David Entwistle, San Carlos, CA (US);

Rama Voladri, Pleasanton, CA (US);

Ravi David Garcia, Los Gatos, CA (US);

Jeffrey C. Moore, Westfield, NJ (US);

Shane Grosser, Princeton, NJ (US);

Birgit Kosjek, Westfield, NJ (US);

Matthew Truppo, Ocean Township, NJ (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2005.12); C12P 17/12 (2005.12);
U.S. Cl.
CPC ...
C12N 9/0071 (2012.12); C12P 17/12 (2012.12); C12Y 114/11 (2012.12); C12Y 114/11002 (2012.12);
Abstract

The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.


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