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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11760981 B1

PDFFull Text
Date of Patent:
Sep. 19, 2023

Filed:

Jul. 17, 2019

Engineered glycosyltransferases and steviol glycoside glucosylation methods

Applicants:

Codexis, Inc., Redwood City, CA (US);

Tate & Lyle Ingredients Americas Llc, Hoffman Estates, IL (US);

Inventors:

Jonathan Vroom, South San Francisco, CA (US);

Stephanie Sue Galanie, Knoxville, TN (US);

Jack Liang, San Mateo, CA (US);

Joyce Liu, Fremont, CA (US);

Nikki Dellas, Mountain View, CA (US);

Melissa Ann Mayo, Foster City, CA (US);

David Entwistle, San Carlos, CA (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:

Codexis, Inc.

Primary Examiner:

Suzanne M Noakes

Int. Cl.
CPC ...
C12N 9/10 (2006.01); C07H 15/252 (2006.01); C12P 19/56 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1062 (2013.01); C07H 15/252 (2013.01); C12N 9/1048 (2013.01); C12P 19/56 (2013.01); C12Y 204/01013 (2013.01);
Abstract

The present invention provides engineered glycosyltransferase (GT) enzymes, polypeptides having GT activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. The present invention provides engineered sucrose synthase (SuS) enzymes, polypeptides having SuS activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. The present invention also provides compositions comprising the GT enzymes and methods of using the engineered GT enzymes to make products with β-glucose linkages. The present invention further provides compositions and methods for the production of rebaudiosides (e.g., rebaudioside M, rebaudioside A, rebaudioside I, and rebaudioside D). The present invention also provides compositions comprising the SuS enzymes and methods of using them. Methods for producing GT and SuS enzymes are also provided.

Find Patent Forward Citations

Vroom, Jonathan. (2023). Engineered glycosyltransferases and steviol glycoside glucosylation methods (U.S. Patent No. 11760981). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11760981

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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