The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2025
Filed:
Apr. 23, 2020
Applicant:
Codexis, Inc., Redwood City, CA (US);
Inventors:
Xiang Yi, San Carlos, CA (US);
Oscar Alvizo, Fremont, CA (US);
Ravi David Garcia, Los Gatos, CA (US);
David Entwistle, San Carlos, CA (US);
Charlene Ching, San Jose, CA (US);
James Nicholas Riggins, San Francisco, CA (US);
Nandhitha Subramanian, Cambridge, GB;
Assignee:
Codexis, Inc., Redwood City, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01); C12N 1/20 (2006.01); C12N 15/72 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12N 1/20 (2013.01); C12N 15/72 (2013.01);
Abstract
The present application provides engineered glucose dehydrogenase polypeptides having imine reductase activity, polynucleotides encoding the engineered polypeptides, host cells capable of expressing the engineered polypeptides, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.